Searching with PICO

PICO

P - Patient Population (age, gender, health, medications, access, conditions)

I - Intervention/Exposure

C - Comparison group

O - Outcome predicted

t - time frame

PICO Breakdown

Patient

What are their most important characteristics?

primary problem
disease state
co-existing condition

Describe your patient specifically:

Sex
Age
Ethnicity
Socioeconomic factors

ALWAYS include this piece in your search.

Intervention

What do you want to do for the patient?

Order a test
Prescribe a drug
Order a procedure

Other considerations:

Main intervention
Prognostic factors
Exposures

Almost always include this piece in your search.

Comparison

What is the alternate intervention, if any?

A different drug
No medication
A Placebo
A different test
A different procedure

It is less common to include this piece in a search.

Outcome

What are you hoping to achieve, measure, or change for the patient?

Alleviate symptoms
Improve test results
Reduce adverse events
Improve function

Could also be the result NOT desired.

Sometimes include this piece in your search.

Sample PICO Questions

Example Questions

1. In adults with COPD (patient), does pulmonary rehabilitation (intervention) reduce the rate of COPD-related hospitalization (outcome)?

2. Is the use of intravenous magnesium sulfate (intervention) more effective than nebulized magnesium sulfate (comparison) for improving the pulmonary function (outcome) of children with acute asthma (patient)?

3. Does hand washing (intervention) among healthcare workers (population) reduce hospital acquired infections (problem)?

Where do I find which type?

Additional Help